Background: Accurate anteroposterior measurement of the jaw relationship is critically important in Orthodontic(s) diagnosis and treatment planning. ANB angle, WITS analysis, and BETA angle, etc. have been defined and used in dental education but are relatively inaccurate for the evaluation of AP discrepancies due to dependency on various factors. Clinical studies/trials aiming to find one reliable indicator among these angles will help the clinician to assess any skeletal discrepancy accurately and reliably. This study aims to compare W angle and YEN angle in class I, II, and III malocclusions and to assess their comparative accuracy for measuring skeletal dysplasia. Methods: Lateral cephalogram of 45 subjects aged between 14-30 years were taken from the archives of the Department of Orthodontics. They were divided into Class I, Class II, and Class III skeletal subgroups based on ANB and BETA angle with 15 samples in each subgroup. W Angle and YEN angle were calculated and correlated between each other and in the three skeletal subgroups. Results: A significant correlation was observed between W angle and YEN angle and the highest correlation was for YEN angle followed W angle. Correlation for class II malocclusion is more compared to class I followed by class III malocclusion. Conclusion(s): The YEN angle was found to be the most preferred angle to be computed to assess and differentiate Class I, Class II, and Class III skeletal dysplasia.