Background: A key to successful endodontics and a major goal of contemporary nonsurgical root canal treatment is to seal completely, both the apical and coronal avenues of potential leakage and maintain the disinfected status reached by the chemical and / or mechanical cleaning, to prevent reinfection and percolation of bacterial substrates , allowing the periodontium to maintain its integrity and to achieve healing. Aim of the study: To compare efficacy of different obturation techniques. Materials and methods: The present study was conducted in the Department of Endodontics and Conservative Dentistry of the Dental institution. We selected 40 permanent maxillary central incisors with single canal and completed apex formation. We excluded teeth with morphological anomalies and multiple root canals to avoid any bias in the results. For the preparation of root canals, access cavity was made and the canal was located using a #8 K-file. After the canals were located, we cut the crowns of the teeth such that the working length of the canal was standardized at 22 mm for all teeth. The biomechancal preparation of the canals was done using K-files. After completion of the biomechanical preparation of the canal, the teeth were randomly grouped into two groups, Group A and B, with 20 teeth in each group. Results: Mean gutta percha weight in Group A which were obturated with mechanical lateral condensation technique was 11.36 + 1.2 g. Mean gutta percha weight in Group B which were obturated with conventional lateral condensation technique was 8.9 + 1.6 g. Conclusion: Within the limitations of the present study, it can be concluded that mechanical lateral condensation and Conventional lateral condensation techniques are quite effective in sealing the root canal; however, our study has demonstrated that MLC is superior to CLC. Keywords: Obturation, root canal, lateral condensation, endodontic.