Aim of the Study: The Aim of this study was to evaluate and compare the relationship between severity of asthma and malocclusion prevalence in children. Material & Methods: 50 asthmatic children in the age group of 5-10 years were enrolled in this study. Children who had orthodontic treatment or were currently wearing an orthodontic appliance with history of Asthma were excluded from the study. Malocclusion was measured using Dental Aesthetic Index (DAI) in accordance with WHO recommendations. Results: The distribution of subjects according to their malocclusion status was found to be significantly different among groups according to severity of asthma. As the severity increases, the frequency of Normal/Minor Malocclusion cases also significantly increases, when mean overall DAI scores of subjects having mild, moderate or severe asthma were compared, then no statistically significant difference was found. Conclusion: The present study proves a strong relationship between severity of Asthma & Malocclusion in children. Key words: Asthma, Malocclusion, Dental Aesthetic Index.