Background: A key to successful endodontics and a major goal of contemporary nonsurgical root canal treatment is to seal completely both the apical and coronal avenues of potential leakage and maintain the disinfected status reached by the chemical and mechanical cleaning to prevent reinfection and percolation of bacterial substrates, allowing the periodontium to maintain its integrity and to achieve healing. Aim of the study: To compare two different techniques of gutta percha condensation in endodontic canals. Materials and methods: The study was conducted in the Department of Conservative Dentistry and Endodontics of the Dental Institution. For the study, we selected 40 extracted permanent maxillary central incisors with single canal and completed apex. Teeth with morphological and developmental anomalies were excluded from the study. We kept the teeth immersed in normal saline from the day of extraction to the day commencing the study. Results: A total of 40 extracted maxillary central incisors were used in the study. Teeth were randomly grouped into two groups with 20 teeth in each group. Teeth were weighed before and after the completion of obturation. The difference between initial and final weight after obturation of teeth was calculated and a list was formulated for both the groups. The mean weight of gutta percha for Group LC was 13.65 + 1.25 g and Group MLC was 10.11 + 0.9 g. Conclusion: Within the limitations of the study we conclude that Mechanical lateral condensation technique is superior to conventional lateral condensation technique in obturation of endodontic canals with gutta percha cones. Key words: Endodontic canals, Root canals, Gutta percha.