Background: Acute diarrhea remains one of the most important health issues worldwide, with high morbidity and mortality rates, accounting for more than two million deaths annually. Hence; we planned the present study to assess and compare the efficacy of Nitazoxanide and probiotics for the treatment of acute rotavirus diarrhoea in paediatric patients. Materials & methods: A total of 50 patients with acute rotavirus diarrhoea were included in the present study. All the patients were divided into two study groups with 25 patients in each group. Group 1 included subjects who were treated with Nitazoxanide therapy while group 2 included subjects who were treated with probiotics therapy. Microbial stool cultures were used as a standard for assessing the efficacy of both the treatment regimens. Collection of stool specimens was done in aseptic storage bins and was transported to central laboratory for further assessment. Yield of any enteric pathogens from stool samples was considered to be a positive stool culture. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: Success rate among both the study groups was found to be in approximation with each other. Non- significant results were obtained while comparing the success rate of both the treatment therapies. Conclusion: Both the treatment regimens are having equal effective therapeutic potential in treating diarrhoea in paediatric patients.
Key words: Antibiotic, diarrhoea, Regime

Received: 12 May, 2019                                   Revised: 18 June, 2019                             Accepted: 21 May, 2019

Corresponding author: Dr. Savleen kaur Gill MBBS, Private Consultant, Ludhiana (Punjab), India

This article may be cited as: Gill SK. Comparative evaluation of efficacy of Nitazoxanide and probiotics for the treatment of acute rotavirus diarrhea in paediatric patients: An observational study. Int J Res Health Allied Sci 2019; 5(3): 91- 93.