Background: ART has proved efficacious in reducing mortality and morbidity related to Human Immunodeficiency Virus (HIV) infection; however, is also associated with both short- and long-term drug-induced toxicities. Hence; we planned the present study to assess various adverse reactions of antiretroviral drug regimens. Materials & methods: We planned the present study to evaluate of various adverse reactions of antiretroviral drug regimens. A total of 50 patients who attended the tertiary care hospital branch of the hospital were included in the present study.Recording of the complete demographic, clinical and medical details of all the patients was done. Complete biochemical investigations of all the patients were carried out and the results were tabulated in the Microsoft excel sheet. All the results were analyzed by SPSS software. Chi-square test was used for assessment of level of significance. Results: Most common drug reactions observed in the present study were anaemia, thrombocytopenia, neutropenia, pruritus, vomiting, peripheral neuropathy and hepatitis. Among these adverse effects, anaemia, hepatitis and pruritus were the most common side effects encountered in the present study. Conclusion: Significant amount of adverse drug reactions are associated with ART, among which haematological associated ADR are the most common.
Key words: Adverse drug reaction, Antiretroviral drug therapy

Corresponding Author: Dr. Roohi Sharma, Demonstrator, Department of Pharmacology, GMC, Jammu,  J & K, India
This article may be cited as: Sharma R, Gilani Z, Sundas. Assessment of various adverse drug reactions of antiretroviral therapy (ART): A tertiary care centre study. Int J Res Health Allied Sci 2018; 4(3):38-40.