Background: Oral submucous fibrosis (OSMF) is a chronic debilitating disease and a premalignant condition of the oral cavity. Copper content of areca nut was found to be more than the content in nuts in snacks consumed by the population. Hence; we planned the present study to assess the mucosal copper levels in OSMF patients. Hence; we planned the present study to assess the mucosal copper levels in OSMF patients.  Materials & methods:We planned the present study for assessing mucosal copper levels in OSMF patients. We included a total of 20 OSMF patients and 20 normal controls were included in the present study. Estimation of the copper content was achieved by the colourimetric method. We analyzed all the results by using SPSS software. Results: Mean mucosal copper levels among OSMF patients were found to be significantly higher in comparison to the normal controls. Conclusion: In the pathogenesis of oral submucous fibrosis, copper does play a significant role.
Key words: Copper, Oral submucous fibrosis.

Corresponding Author: Dr. Nuzhat Nabi, Postgraduate Student, Department of Oral Medicine and Radiology, Jaipur Dental College, Jaipur, Rajasthan, India

This article may be cited as: Nabi N, Desai VD, Phore S , Malik AR. Role of Copper in the Pathogenesis of Oral Submucous Fibrosis: A Comparative Study. Int J Res Health Allied Sci 2018; 4(1):63-65.