Aim: This study set out to compare the percentage of a root canal filled with gutta-percha (PGFA) between canals filled using the Thermafil method, canals filled using Warm Vertical Condensation (WVC), and canals filled using Cold Lateral Condensation (CLC), all of which omitted the use of sealers. In order to accomplish this, microscopical inspection of root canal cross-section was performed. Materials and methods: When the treatment was over, we were left with 90 permanent teeth, each of which only had one root. After having the crowns of the teeth removed, the samples were randomly divided into three groups, each containing a total of thirty specimens. This research found that there are three unique clusters based on the obturation techniques used. The Thermafilobturation group, the warm vertical condensation group, and the cold lateral condensation group all performed their respective obturation techniques. Results: Table 1 summarizes the average percentage of gutta-percha filled area in the apical third of root canals for each of the three methods (Thermafil, WVC, and CLC). The respective methods yielded these findings. Group A specimens treated with Thermafil technology showed the highest mean PGFA (Periapical Gutta-Percha Filling Area), as determined by the study. Group B (WVC) used the second highest average PGFA and had the second highest PGFA of the groups. Group C, on the other hand, followed the CLC method and had the smallest percentage of PGFA. Conclusion: The results of the current study demonstrate that both the warm vertical condensation technique and the cold lateral condensation strategy result in significantly lower PGFA compared to the ThermafilObturation method.