Background: Coronary artery disease is a major cause of death as well as an economic burden to both developed and developing countries. The present study was conducted to study correlation between BMI, Hba1c and fasting lipid profile in patients presenting with acute coronary syndrome and their relationship with CVD Risk. Materials & Methods: 58 diabetics of both genders on treatment with either insulin or oral drugs or both, presenting with acute coronary syndrome were investigated with ECG, 2D-ECHO, glycosylated haemoglobin and fasting lipid profile. Diagnosis of ACS was made on the basis of clinical features, ECG and 2D-ECHO. Results: There were 38 males and 20 females, ECG findings showed STEMI in 26, NSTEMI in 14 and USA in 18 cases. CAG showed SVD in 13, DVD in 28 and TVD in 17 cases. Alcohol history was seen in 22, hypertension in 40, smoking in 24. HbA1C level 6.5- 8.4% in CAG with single vessel and multiple vessels was seen among 10 and 12 and >8.5% in 6 and 30 subjects respectively. SVD and multiple vessels had HDL <40 seen in 4 and 36, >40 in 12 and 6. LDL <100 was seen in 5 and 8 and >100 in 11 and 34 subjects. The difference was significant (P< 0.05). Conclusion: There is strong correlation between HbA1c and dyslipidaemia, with severity of coronary artery disease. HbA1c, total cholesterol, LDL cholesterol are directly proportional and HDL cholesterol is inversely proportional to the severity of coronary artery disease. Key words: Coronary artery disease, Dyslipidaemia, Diabetes