Background: Cardiorenal syndrome (CRS) is defined as a complex pathophysiological disorder of the heart and the kidneys in which acute or chronic dysfunction in one organ may induce acute or chronic dysfunction in the other organ. Hence; the present study was undertaken for assessing the profile of patients with Cardiorenal syndrome in critical care/ICU. Materials & methods: A total of 100 patients with diagnosis of CRS admitted to critical care/intensive care unit were enrolled. Complete demographic and clinical details of all the patients were obtained. A Performa was made and clinical along with etiologic data of all the patients was recorded. Presence of any association comorbidity was also recorded separately. Radiographic analysis was done and findings were recorded separately. All the results were summarized in Microsoft excel sheet and were analysed by SPSS software. Results: Mean age of the subjects was 53.6 years. Total 52 percent of the patients had type 1 CRS, 10 percent had type 2, 5 percent had type 3, 4 percent had type 4 and 29 percent had type 5 CRS respectively. Diabetes and acute kidney injury as co-morbid condition was seen in 27 percent and 15 percent of the patients respectively while septicaemia and acute coronary syndrome were seen in 15 percent and 6 percent of the patients respectively. Hypertension was seen in 42 percent of the patients. Conclusion: Type 1 and Type 5 are the most common type of CRS encountered. Key words: Cardiorenal syndrome, Critical care, Intensive care unit