Background: Liver fibrosis results from the perpetuation of the normal wound healing response resulting in an abnormal continuation of fibrogenesis. Physicians involved in the care of patients with cirrhosis recognize that the development of renal dysfunction is associated with significant morbidity and mortality. Hence; the present study was undertaken for assessing renal profile in liver cirrhosis patients. Materials & methods: A total of 50 patients with cirrhosis of liver were enrolled. Physical examination was done to look for any evidence of renal involvement. Patients were graded according to Child Pugh Grade with Grade A indicating minimal severity while grade C indicating maximum severity. Results: Mean blood urea levels and serum creatinine levels were found to be 39.3 mg/dL and 1.5 mg/dL respectively. While assessing statistically, a significant positive correlation was observed between deranged renal profile and severity of liver cirrhosis. Conclusion: Renal profile is severely altered with increasing severity of cirrhosis of liver. Key words: Liver, Cirrhosis, Renal