Background: Cholecystectomy is the treatment of choice for symptomatic gall stone disease. As the technique became a routine procedure, modifications were made in order to make it less invasive and more cosmetic. Initially, a 3-port LC (LC3P) instead of the standard 4-port LC (LC4P) approach was preferred when the anatomy was clearly visualized at the time of the initial laparoscopic evaluation and no technical difficulties were anticipated. Hence; under the light of above obtained data, we compared the outcome of 3-port laparoscopic cholecystectomy versus standard 4-port laparoscopic cholecystectomy. Materials & methods: The present study was conducted with the aim of comparing the outcome of 3-port laparoscopic cholecystectomy (LC) versus standard 4-port laparoscopic cholecystectomy. 100 patients undergoing laparoscopic cholecystectomy were enrolled in the present study. All the patients were broadly divided into two study groups with 50 patients in each group as follows: Group A which included patients undergoing 3-port LC and Group B which included patients undergoing 4-port LC. Follow-up was done and outcome was compared. All the results were analysed by SPSS software. Results: Mean operative time among patients of group 1 and group 2 was 63.8 minutes and 45.9 minutes respectively. Significant results were obtained while comparing the mean operative time among the two study groups. Mean VAS among the patients of group 1 and group 2 at one day of surgery at 6 hours was 6.35 and 7.85 respectively. Mean VAS among the patients of group 1 and group 2 at discharge was 3.16 and 5.26 respectively. Mean VAS among the patients of group 1 and group 2 at one week of follow-up was 2.11 and 3.95 respectively. While comparing statistically, it was seen that mean VAS was significantly higher among the patients of group 2. Conclusion: The three port technique is as safe as the standard four port for laparoscopic cholecystectomy. The main advantages of the three port technique are that it is less painful, safe, and leaves few scars. Key words: Laparoscopic cholecystectomy, Three port, Four port