An understanding of the muscles of face is important to successful complete denture construction. These muscles may be observed at work by the dentist when he first views his patient and that patient begins to speak. An understanding of its prosthodontic significance enables the dentist to employ postoperative vision in the treatment planning stage which can minimize denture failures. Hence, in this article an attempt is made to review all the muscles and their activity and how they can be manipulated for success of prosthodontic treatment