Complete-denture therapy involves a complex interplay between the biologic and technical limitations. Fabrication of successful complete dentures is dependent on technical, biological, and psychological interplay between the clinician and the patient. The overall success of complete denture therapy depends on patient’s comfort and acceptance of the dentures interplay between the clinician and the patient. Identification of post insertion complaints in different types of prosthesis would be very supportive to developing strategies to prevent and manage these more effectively by reducing all negative factors associated with these complaints. Hence, this article reviews about post insertion instructions, problems and management in denture patients. Key words: Denture, Management, Insertion