Background: The present study was conducted to compare the surface roughness of glazed and chair-side polished monolithic zirconia. Materials & Methods: 35 discs were divided into 5 groups of 7 specimens each. Group I was roughened, unpolished and unglazed. Group II (Positive Control) was glazed without prior roughening, group III was roughened and polished with eZr polishing kit, Group IV was roughened and polished with Optra fine ceramic polishing kit and Group V was roughened and glazed. The surface roughness (Ra) values (μm) were measured. Results: The mean surface roughness value in group I was 1.25 μm, in group II was 0.54 μm, in group III was 0.49 μm, in group IV was 0.48 μm and in group V was 0.57 μm. The difference was significant (P< 0.05). Conclusion: The present study was conducted to compare the surface roughness of glazed and chair-side polished monolithic zirconia. Key words: Polishing system, Surface roughness, Zirconia.