Cancer is a disease involving complex multiple sequential irreversible dysregulated processes showing metastasis that results in morbidity and mortality. Metastasis to the oral region are uncommon and account for about 1% of the oral malignant tumors and it may occur in the oral soft tissue or jaw bones. In 25% of cases, oral metastasis were found to be the first sign of the metastatic spread and in 23% it was the first indication of an undiscovered malignancy at a distant site. So we can say that oral cavity is the mirror of whole body. Oral lesions and manifestations suspect the possibility of metastasis from distant sites and that initiate the necessary investigations. This article has emphasised on various pathogenetic mechanisms related to tumours metastasizing to oral cavity.
Key words: Metastasis, Jaw tumours, Chemotherapy.