Several scientific literature has been published since the outbreak of the novel coronavirus disease 2019 (COVID-19)which is caused by SARS-CoV-2, few published articles called the attention to the oral cavity as the potential route of infection, leading to various implications for dental practice and the use of saliva as a diagnostic tool for the COVID-19. In this article we would review the available literature on the salivary glands, salivary flow and oral manifestations in the context of SARS-CoV-2 infection. Keywords: Sars-CoV-2, Salivary glands, Salivary outcome, Oral manifestations, infectious diseases.