Background: Metabolic effects of HIV infection such as hypertriglyceridemia are well recognized. The present study assessed the prevalence of dyslipidemia in HIV patients on HAART. Materials & Methods: This study done on 50 patients (male- 36, female- 14) who were diagnosed HIV seropositive, attending the outpatient department or admitted in the Medicine ward of Government Medical College and associated Guru Nanak Dev Hospital, Amritsar. Lipid profile estimation in the fasting state of fifty normotensive, non-diabetic, and non-obese HIV positive patients was done. Results: The mean CD 4 level in males was 356.13 ± 173.17 and in females was 395.35 ± 208.02. The difference was non- significant (P> 0.05). The mean total cholesterol in males was 187.47 mg/dl and in females was 201.42 mg/dl, triglyceride in males was 221.41 mg/dl and in females was 235.5 mg/dl, LDL was 108.2 mg/dl and in females was 122.2 mg/dl, HDL was 33.9 mg/dl in males and 37.6 in females and VLDL was 44.2 mg/dl in males and 47.1 mg/dl in females. The difference was significant (P< 0.05). Dyslipidemia was seen in TC in 16 (32%) and HDL in 40 (80%). Conclusion: Lipid abnormalities are common in treatment-naïve HIV-infected patients, even in the absence of major host-related risk factors for dyslipidaemia. The combination of hyper-triglyceridemia and low HDL-C is the most consistent abnormality. HIV-infected patients should, therefore, be routinely screened for lipid disorders before commencement of ART, and those found to have dyslipidaemia, should be appropriately treated. Key words: Dyslipidemia, Lipid, HAART