Background: The relationship of thyroid hormonal abnormalities and cardiovascular disease goes well beyond the risk of atherosclerosis in association with hypothyroidism and the risk of atrial fibrillation in persons with hyperthyroidism. Hence; we planned the present study to assess the thyroid profile of patients with acute coronary syndrome. Materials & methods: This was a cross-sectional study in which 50 patients with acute coronary syndrome that presented to the emergency department of Guru Nanak Dev Hospital Amritsar. On admission, detailed history and clinical examination of the patients was done. Samples were collected and were assessed for routine baseline blood investigations. For serum thyroid hormone profile was measured by Enzyme linked immunosorbent assay (ELISA) technique. Results: The patients with subclinical hypothyroidism and subclinical hyperthyroidism were 3 (17.6%) and 1 (5.9%) respectively whereas 13 (76.5%) number of patients were suffering from Sick Euthyroid Syndrome. Mortality was found to be present in the patient of the Sick Euthyroid Syndrome group only. Conclusion: The clinicians have to consider thyroid function test for predicting the prognosis in patients of acute coronary syndrome particularly patients having sick euthyroid syndrome
Key words: Acute coronary syndrome, Thyroid.

Received: 5 January  2019                                       Revised: 25 January 2019                              Accepted: 28 January 2019
Corresponding author: Dr. Sukhdeep Singh, Department of Medicine, GMC Amritsar, Punjab, India

This article may be cited as: Chand G, Sharma R, Charan S, Singh S, Kaur A, Sood D. Thyroid function evaluation in patients of acute coronary syndrome and its prognostic significance. Int J Res Health Allied Sci 2019; 5(1):72 -75.