Background: Dry socket, is the most common complication following a dental extraction and one of the most studied complications in dentistry. Hence; we planned the present study to assess and compare the efficacy of topical application of chlorhexidine digluconate with topical application of combination of Iodoform and Butylparaminobenzoate in the management of dry socket. Materials & Methods: We planned included comparison of the efficacy of topical application of chlorhexidine digluconate with topical application of combination of Iodoform and Butylparaminobenzoate in the management of dry socket. A total of 50 dry socket patients were included in the present study and were broadly divided into two study groups as follows: Group A: Included patients treated with chlorhexidine digluconate, Group B: Included patients treated with combination of Iodoform and Butylparaminobenzoate. All the results were analyzed by SPSS software.  Results: Pain disappeared from all the candidates of subjects of group B on day 5, while in group A, disappearance of pain occurred on day 5. Conclusion: In managing dry socket patients, efficacy of Iodoform and butylparaminobenzoate combination is more in comparison to chlorhexidine digluconate gel.
Key words: Alveolar osteitis, Dry socket, Iodoform