Background: The pathogenesis of the oral submucous fibrosis (OSMF) is not well established; however, epidemiological evidence strongly suggests an association between areca nut and oral OSMF. Hence; we planned the present study to assess the role of serum copper and zinc levels in OSMF patients. Materials & methods: In the present study, we included patients that were diagnosed histopathologically as Oral Submucous Fibrosis (OSMF).  A total of 50 subjects were included in the present study, out of which, 25 were of OSMF and 25 were normal control. Patients were called in the morning time, and samples were taken and were sent to laboratory for estimation of serum copper and zinc levels. All the results were evaluated by SPSS software. Results: We observed significant results while comparing the mean serum copper levels and zinc levels in OSMF patients and normal controls. Conclusion: Copper and zinc do play a significant role in the pathogenesis of OSMF.
Key words: Copper, Oral submucous fibrosis, Zinc

Corresponding Author: Dr.Jasmin Singh, Consultant Dentist, Department of health & medical education, Govt. of J & K, India

This article may be cited as:Singh J, Singh S.Estimation of serum copper and zinc levels in oral submucous fibrosis patients: A biochemical study. Int J Res Health Allied Sci 2018; 4(1):102-104.