Aim: To study the combined periodontal and orthodontic treatment with fixed appliances and clear aligners in patients with periodontitis. Materials and methods: This study screened 50 patients (26 men, 24 women) with a mean age of 37.2 years (range: 20–50). All participants had chronic periodontitis and were systemically healthy non-smokers, except for one patient. Exclusion criteria included systemic diseases, bone metabolism disorders, steroid use, active infections, head or neck radiation history, and pregnancy. Data analysis was done using SSPS software. Results: The study included a total of 50 patients, with ages ranging from 20 to 50 years (mean ± SD: 35 ± 8.7 years). The sample comprised 26 males and 24 females. Regarding the type of irregularity, 34 patients exhibited crowding, 10 had spacing issues, and 6 presented with pathologic migration. The severity of irregularity varied, with 2 patients classified as Grade 1, 5 as Grade 2, 20 as Grade 3, 15 as Grade 4, and 8 as Grade 5. Orthodontic treatment methods included fixed appliances for 32 patients and clear aligner treatment for 18 patients. Among the participants, 8 had generalised slight chronic periodontitis, 32 had generalised moderate, and 10 had generalised severe periodontitis. Surgical interventions varied, with 36 patients not requiring regenerative surgery, while 8 underwent pre-orthodontic surgery and 6 received post-orthodontic surgery. Conclusion- While both CA and FA can maintain periodontal health with proper hygiene, some evidence suggests CA may offer slight advantages in plaque control and probing depth. However, due to limited sample sizes, further research is needed for definitive conclusions. Keywords: orthodontic, aligner, periodontitis