Background:The present study was conducted for assessing and comparing flexural strength in three types of denture base resins. Materials & methods:The present study was conducted for assessing serum c reactive protein levels in peri-implantitis patients. 60 acrylic specimens were prepared. Based on the type of acrylic resin used, the specimens were divided into three groups with 10 specimens each. They were Group 1 - conventional denture base resins, Group 2 - high impact denture base resins, and Group 3 - glass reinforced denture base resins. Each group was subjected to flexural strength evaluation.Flexural strength of the samples was accessed using the universal testing machine. The results were recorded and compared using SPSS software. Results:Mean flexural strength of Conventional PMMA group, High impact PMMA and E-glass PMMA was 105.38 MPa, 135.9 MPa and 153.8 MPa respectively. While comparing the results, significant results were obtained.Conclusion: The flexural strength values of heat polymerized PMMA were considerably enhanced by reinforcements.