Aim - The aim of case report is CBCT evaluation of periapical healing after using bioceramic based retrograde filling material i.e., Angelus Bio-C repair and Endosequence BC RRM. Material and method - This report includes two cases of maxillary anterior teeth with periapical lesion. These cases were diagnosed using IOPA and CBCT. After careful diagnosis root canal treatment followed by apicoectomy was performed with placement of retrograde filling materials i.e Angelus Bio-C repair and Endosequence BC RRM. Long term followup was done to assess the periapical healing. Conclusion – Bioceramic material have better healing and ability to induce biomineralization. Keywords: Endosurgery; Apicoectomy; Angelus Bio C Repair; Endosequence BC RRM; CBCT