Background: To assess the effects of smoking on common carotid intima-media thickness. Materials & methods:In total, 50 smokers who were currently smoking and 50 non-smokers were included in the study. Individuals who had smoked during the last month or had consumed about 100 cigarettes during their lifetime were classified as current smokers. Any thickness of CIMT greater than 0.8 mm was considered abnormal. Every outcome was entered into a Microsoft Excel spreadsheet, and then SPSS software was used for statistical analysis. The student t test is employed to assess the degree of significance. Results:The subjects in the CIMT group ranged in age from 43.5 to 48.5 years on average. Males made up the majority of the subjects in both research groups. The current smokers' and non-smokers' mean CIMT values were 0.645 and 0.540, respectively. Conclusion:Smoking causes morphological changes in CCA, as evidenced by changed CIMT. Keywords:Smoking, Carotid Intima-Media.