Background: Provision of adequate safe blood is challenging in developing countries due to the paucity of voluntary blood donors, poor facilities for storage and blood component preparation as well as inappropriate blood ordering and utilization. Hence; the present study was undertaken for assessing transfusion practices in a known population. Materials & methods: The present study was undertaken for assessing transfusion practices in a known population. All the data of patients who underwent elective or emergency procedures, for which blood was ordered, were analyzed. Patients’ age and sex, diagnosis, type of procedure performed, pre-procedure haemoglobin level and number of blood units required to be cross matched and transfused were obtained. The blood which was cross matched but not transfused was considered as wasted. All the results were recorded in Microsoft excel sheet and were analysed by SPSS software. Results: 57 percent of the patients belonged to the age group of more than 40 years. 59 percent of the patients were males while the remaining were females. Total units of blood prepared were 445 and all the 445 units of blood were cross-matched. Total units of blood transfused were 312 while total units of blood wasted were 133. Conclusion: Although blood transfusion is a life-saving measure for many patients, it should be restricted to patients who are in real need for transfusion. Key words: Transfusion, Practices