Volume 7 Issue 1 (January - February), 2021

Original Articles

Assessment of efficacy of two different treatment regimes in treating diarrhoea among Pediatric subjects
Mohit Sharma, Jyoti Bhartiya

Background: Acute diarrhoea is defined as the production of three or more watery stools a day for less than 14 days. In non-severe acute diarrhoea of gastroenteritic origin, these stools do not contain visible amounts of blood or mucus. The present study compared two different treatment modalities for pediatric diarrhoea. Materials & Methods: 68 children age below 5 years with diarrhoea of both genders were divided randomly into 2 groups of 34 each. Group I patients were prescribed oral Racecadotril three times a day and group II was prescribed probiotics (placebo). Comparison of stool output was done in both groups. Presence of rotavirus in stool was also detected. Results: Group I had 18 patients in age group 0-3 years and group II had 17 and age group 3-5 years had 16 in group I and 17 in group II. Stool output in rotavirus positive found to be 142.6 mg in group I and 192.4 mg in group II and in rotavirus negative it was 96.2 mg in group I and 89.5 mg in group II. The difference was significant (P< 0.05). Conclusion: Oral Racecadotril found to be effective in reducing stool output in children with diarrhoea as compared to probiotics. Key words: Diarrhoea, Probiotics, Racecadotril

 
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