Volume 5 Issue 1 (January-February, 2019)

Original Articles

A Study of Profile of Acute Coronary Syndrome in Young Patients in Tertiary Care Hospital in Punjab- A Clinical Study
Avtar Singh Dhanju, R.K Sharma, Ajay Chhabra, Amandeep Singh Dhanju, Priya Sharma, Jagbir Singh

Acute coronary syndrome (ACS) is believed to more clearly reflect the disease progression associated with myocardial ischemia and includes Unstable angina (UA),Non ST elevation myocardial infarction(NSTEMI) and ST elevation myocardial infarction (STEMI). The present study was conducted on 100 patients of both genders less than 45 years of age presenting with the diagnosis of Acute Coronary Syndrome. Patients presenting with serial ECG – ST segment elevation in more than 2 contiguous leads, ST segmentdepression > 1 mm in 2 contiguous leads and/or T-wave inversion during chest pain, episodes or any bundle branch block (new onset LBBB or RBBB) or AV block were enrolled in study .A correlation of history, clinical features, risk factors, ECG,Echocardiography,cardiac biomarkers during hospital stay with the severity ofACS were evaluated.ST elevation MI formed the major subgroups (46%) followed by Unstable Angina (33%) and Non ST elevation MI (21%). There was positivecorrelation of smoking (r- 0.421, p- 0.01), sedentary lifestyle (r- 0.405, p- 0.01), hypertension (r- 0.315, p- 0.05) and dyslipidemia (r- 0.287, p- 0.001) in patients with ACS. Diabetes mellitus (r- 0.543, p- 0.12) and family history of ischaemic heart disease (r- 0.642, p- 0.81) had no positive correlation.Acute coronary syndromes are a major cause of concern in the present-day world particularly when it happens in a younger age group population. It poses a huge economic burden to the society also with loss of life and morbidity at a productive age group.
Key words: Acute coronary syndrome, Non ST elevation MI, Unstable Angina.

Received: 5 January  2019                                 Revised: 25 January 2019                        Accepted: 28 January 2019
Corresponding author: Dr R.K Sharma, Professor, Department of Medicine, GMC Amritsar, Punjab, India

This article may be cited as: Dhanju AS, Sharma RK,  Chabbra A,  Dhanju AS, Sharma P, Singh J. A Study of Profile of Acute Coronary Syndrome in Young Patients in Tertiary Care Hospital in Punjab- A Clinical Study. Int J Res Health Allied Sci 2019; 5(1):64 -68.

 
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