Volume 7 Issue 4 (July-August), 2021

Original Articles

Evaluation of renal profile in liver cirrhosis patients
Anmol Malhotra, Archana Bhate

Background: Cirrhosis is characterized by fibrosis and nodule formation of the liver, secondary to a chronic injury, which leads to alteration of the normal lobular organization of the liver. Accurate evaluation of the renal function is potentially crucial in liver cirrhosis patients. Hence; the present study was planned for assessing the renal profile in liver cirrhosis patients. Materials & methods: A total of 50 subjects with presence of cirrhosis of liver were enrolled in the present study. For assessment of kidney function serum urea, creatinine, serum sodium and potassium were examined. Severity of liver cirrhosis was assessed in terms of Child Pugh Score. According to this score, patients were graded into Grade A, B and C with A grade indicating minimal severity and C grade indicating maximum severity. All the results were recorded and analyzed by SPSS software. Results: According to Child Pugh Score grading, 36 percent, 38 percent and 26 percent of the patients were of Grade A, grade B and Grade C respectively. Altered renal profile was seen in 18 percent of the patients. Significant results were obtained while correlating severity of liver cirrhosis and renal dysfunction. Conclusion: Significant association exists between severity of liver dysfunction and renal dysfunction. Key words: Renal profile, Cirrhosis

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