Introduction: A drug may be defined as a chemical substance, or combination of substances, administered for the investigation, prevention or treatment of diseases or symptoms, real or imagined. WHO defines an adverse drug reaction as “a response to a drug that is noxious and unintended and occurs at doses normally used in man for the prophylaxis, diagnosis or therapy of disease, or for modification of physiological function. Aim : To evaluate clinical profile of adverse cutaneous drug reactions. Materials & Methods: An observational, cross-sectional single centered study of eighteen-month duration at a tertiary care teaching hospital in north India. Result: A total of 172 patients diagnosed with CADR, fulfilling the inclusion criteria were included in the study. The most frequent drug eruption observed was maculopapular rash 84 (48.83%). The other drug eruptions included urticaria 22 (12.79%), urticaria + angioedema 18 (10.46%), Erythema multiforme 12 (6.97%), Fixed drug eruption 10 (5.81%), Erythroderma 9 (5.23%), Acneiform eruptions 7 (4.06%), Vasculitis 4 (2.32%), Steven’s Johnson syndrome 3 (1.79%), DRESS 2 (1.16%) and Toxic epidermal necrolysis 1 (0.58%) in that order. Conclusion: Cutaneous adverse drug reaction profile in our study were analysed and compared with many other studies conducted earlier in various part of the country. Timely recognition of morphological patterns of cutaneous adverse drug reaction may be very helpful in identifying an offending drug in the setting of multiple drug therapy. Thus, limiting morbidity and mortality in patients. Keywords: Adverse Cutaneous Drug Reactions, maculopapular rash, Urticaria.