Sex hormones have long been considered to play an influential role on periodontal tissues, bone turnover rate, wound healing and periodontal disease progression. They play an important role in periodontal health and disease. For example, puberty, menses, pregnancy, menopause, oral contraceptive use in women periodontal health and hypogonadism in male periodontal health. Hormones are specific regulatory molecules that have potent effects on the major determinants of the development and the integrity of skeleton and oral cavity including periodontal tissues.
The purpose of this review paper is to brief the effects of endogenous sex hormones on periodontium.
Keywords: sex steroids, estrogen, progesterone, testosterone, cyto-differentiation, cytokines.