Volume 7 Issue 5 ( September - October ), 2021

Original Articles

Assessment of histopathologic findings of patients with COVID complications
Dr Gunveen Kour, Dr Andleeb Manhas, Dr Harshy Sharma

Background: COVID-19-associated mucormycosis, an opportunistic fungus that invades rhinal, occipital and cerebral areas, come to light as the pandemic proceeds. Mucormycosis is caused by the fungus Mucor (class Phycomycetes, order Mucorales) that is capable of reaching craniofacial compartments such as paranasal sinuses, pharynx, orbita and intracranial cavity via the spore spread. Hence; the present study was conducted for assessing the histopathologic findings of patients with COVID complications. Materials & methods: A total of 20 patients who had past history of COVID-19 infection and reported with presence of post-COVID Mucormycosis were enrolled. Complete demographic and clinical details of all the subjects were obtained. Biopsy specimens were obtained and histopathologic examination was carried out. Histopathologic findings were analysed and correlated. Results: A total of 20 patients with presence of post-COVID Mucormycosis were enrolled. Mean age of the patients was 52.3 years. Histopathologic finings revealed non-septate hyphae invading blood vessels in 13 cases while it revealed minimally septated broad, ribbon-like hyphae in 7 cases. Conclusion: Mucormycosis is a life-threatening fungal infection, with very high mortality.

 
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